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Experimental example Using erastin-treated A549 cells, we measured intracellular Fe 2+ , ROS, lipid peroxide, glutathione, glutamate release into the extracellular space, and cystine uptake

Preclinical models show activity at 24 weeks

Accordingly, we quantified plasma TG levels

All participants would receive a standardized SSRI regimen and be randomized to adjunctive treatment with standardized extracts of Rhodiola rosea , Ginkgo biloba , Ashwagandha, or matched placebo, with triple blinding maintained across participants, clinicians, and outcome assessors

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