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Some researchers hypothesize that the increased energy expenditure from glucagon activation means less of the caloric deficit needs to come from dietary restriction, which may be less catabolic to muscle tissue

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(PubMed) World Health Organization, UNICEF, ICCIDD

Fortified foods and meat can help ensure adequate B12 intake if eaten as part of a balanced diet rich in B12 sources like fish, dairy products, and meat

The researchers weren't sure why

Im also taking Berberine so I think both work amazing