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[15] [16] Tirzepatide is administered as a once-weekly subcutaneous injection, with doses ranging from 2.5 mg to 15 mg depending on the indication and patient tolerance

rather, this is simply a natural consequence of significant fat loss

These data also support the conclusion that Fab 3F52 directly blocked binding of BMS21, implying that Fab 3F52 occupies partially the orthosteric binding site of the GLP-1R TM domain, which is interesting considering the spatial relationship of the ECD, the antibody and the TM domain

Reductions exceeded 80% with 8 mg and 12 mg

Initial approval lasts six months