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Procedures Participants received subcutaneous semaglutide 2.4 mg or placebo once-weekly for 104 weeks, in addition to standard behavioral intervention, followed by 7 weeks without treatment

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Injection technique Subcutaneous injection is straightforward: Clean injection site with alcohol swab Pinch skin to create a fold Insert needle at 45-90 degree angle Inject slowly Remove needle and apply gentle pressure Common injection sites: abdomen (2 inches from navel), thighs, love handles

Get medical review Fill out a brief intake form and receive a prescriber response in 2-3 days

They found no evidence of increased lipid storage in any non-adipose tissue

That matters if you have trouble absorbing B12 from food or pills, which is more common than most people realize