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Women of childbearing potential should employ reliable contraception during BPC-157 treatment if used clinically, pending establishment of safety in pregnancy

For P450 enzyme inducers, hepatocellular hypertrophy is typically characterized ultrastructurally by proliferation of smooth endoplasmic reticulum (Figure 2) that on HandEstained light microscopy sections is manifested as enlarged hepatocytes with finely granular or ground glass eosinophilic cytoplasm (Figure 3)

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13 See FIGURE 1 for a summary of current recommendations from the ADA for second-line therapy in patients with T2DM