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By focusing on the largest fragment, this metric assesses whether the model has correctly identified the principal retrosynthetic transformation (the core bond disconnection), even if smaller reagents, solvents, or byproducts are missing or incorrect or alternates

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A purified membrane protein from Akkermansia muciniphila or the pasteurised bacterium blunts colitis associated tumourigenesis by modulation of CD8(+) T cells in mice