glp-1 and ampk Exendin-4 exhibits cardioprotective effects against high glucose-induced mitochondrial abnormalities: Potential role of receptor mTOR signaling Cardiovascular protective effects of GLP-1:

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Molecular formula is C10H17N3O6S, molecular weight is 307.32, and purity is 98%HPLC

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Dec 2008;83(12):1373-1381

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The structure of exendin-4 in complex with the N-terminus domain of the human GLP-1R 17 (Protein Data Bank code 3C5T) was then used to rationally guide the location of the cysteines in the -helix of the peptide and in the linker or peptide C-terminus to minimize the impact on receptor binding and to favour disulphide bridge formation in order to reduce propensity to aggregate (Fig