Hinman A, Holst CR, Latham JC, Bruegger JJ, Ulas G, McCusker KP, Amagata A, Davis D, Hoff KG, Kahn-Kirby AH, et al
Working with a healthcare provider who understands this relationship, you can calculate a personalized B12 approach based on your kidney function: normal function allows standard dosing, mild decrease might call for 75% of standard doses, moderate decrease might need 50% of standard, and severe decrease might require 25% of standard with closer monitoring
Comparable evolutionary dynamics occur across solid tumors, including RASMAPK pathway alterations in colorectal cancer, branching resistance in BRAF-mutant melanoma, BRCA1/2 reversion mutations under PARP inhibition in ovarian cancer, and lineage plasticity leading to neuroendocrine differentiation in prostate cancer (121, 122)
doi: 10.3390/nu13072195 77
Association of vitamin B12 deficiency in people with type 2 diabetes on metformin and diabetic peripheral neuropathy Nature article: Shows prolonged metformin use correlates with lower B12 and more severe diabetic neuropathy
The findings showed that SOD medication was safe and improved blood indicators including lactate dehydrogenase and surfactant protein-A in individuals with advanced idiopathic interstitial pneumonias and severe respiratory dysfunction
