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The discovery of epitalon, a tetrapeptide with the amino acid sequence Ala-Glu-Asp-Gly, was a direct result of efforts to develop safe and effective methods for offsetting adverse effects of aging

doi:10.3390/nu8030167 [39] Giuliani C, Bucci I, Di Santo S, et al

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Regulation of vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 in human vascular smooth muscle cells