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The research focus is primarily on connective tissue injuries: tendons, ligaments, muscles, and joints

PMID: 216 YuanXZhouFWangHXuXXuSZhangCet al

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Research Applications PT-141 has been utilized as a molecular probe in controlled experimental systems examining: Central melanocortin receptor pharmacology (MC3R, MC4R) Hypothalamic and limbic circuit characterization Mesolimbic dopaminergic pathway modulation Autonomic nervous system signaling models Neuroendocrine regulatory pathway research Melanogenesis and MC1R-mediated pigmentation signaling Energy homeostasis and metabolic feedback models

In the unilateral ureteral obstruction (UUO) animal model, the administration of deferoxamine (DFO) has been shown to alleviate tubulointerstitial fibrosis