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MET is an oncogene 17,18 , and somatic copy number gains of the C-MET locus are found in almost half of melanomas 19

Together, these findings establish that LCN2 exacerbates ferroptotic death under both basal and iron-overload conditions and that SLC22A17 is a key mediator of LCN2-driven Fe uptake, oxidative stress, and ferroptosis in osteocytes

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