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doi: 10.3389/fphys.2021.660068

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All luciferase assays were done in triplicate

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To confirm whether tig-2 functions as a secreted factor to trigger gonadal longevity, we artificially overexpressed TIG-2::mCherry in the intestine, a tissue with little tig-2 expression (Wang et al, 2022), and found worms lifespan was indeed increased upon the intestinal overexpression of tig-2 (Fig

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