Uncommon and rare adverse effects include cystitis, folliculitis, gastrointestinal infections, hypersensitivity reactions, changes in appetite, depression, insomnia, balance disorders, lethargy, restless leg syndrome, syncope, photophobia, presbyopia, tinnitus, confusion, palpitations, hypertension, hypercholesterolaemia, and weight gain
Separately, a review of five randomised controlled trials presented at ENDO 2026 examined the effects of GLP-1 drugs such as semaglutide and liraglutide on male reproductive health
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It supports detoxification processes, enhances immune function, and contributes to overall cellular health
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Diagnosis requires colonoscopy with mucosal biopsies demonstrating characteristic histologic features: continuous inflammation limited to the mucosa and submucosa, crypt architectural distortion, and increased inflammatory cells
