glp-1 news today 2025 november 5 ISPOR 2025: Exploring reasons for discontinuation How do weight-loss drugs work?

Standardize Clinical Protocols Document your patient intake requirements Set schedules for follow-up and refills Spell out when to change doses, escalate, or refer out Have your medical director sign off on everything Update your protocol when regulations change Keep Clinical Decisions Away from Marketing Pressure Just because patients ask, doesnt mean they get the med

Monitoring recommendations include: Glucose monitoring : Patients should check blood glucose more frequently than usual, particularly if taking insulin or sulfonylureas

Each phase has a specific purpose that they try to elaborate on

Herrett E, Gallagher AM, Bhaskaran K et al (2015) Data resource profile: Clinical Practice Research Datalink (CPRD)

Chemerin enhances insulin signaling and potentiates insulin-stimulated glucose uptake in 3T3-L1 adipocytes

STEP trials: semaglutide The STEP (Semaglutide Treatment Effect in People with obesity) program is the landmark clinical trial series for semaglutide 2.4mg weekly