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The results from this study strongly support the hypothesis that an innovative supplementation protocol involving L-carnitine can improve endurance performance by promoting more efficient fat metabolism, reducing heart rate, and decreasing perceived exertion during high-intensity exercise

The short answer: in some ways, yes, but not across the board

Accelerated Recovery & Performance: Reduces exercise-induced oxidative damage and muscle soreness

"Phenylephrine/Caffeine/Paracetamol dual relief"

Jan 2015;125(1):248-54

By clearing the backlog of unburned lipids in the cytoplasm and feeding them into the mitochondrial furnace, L-Carnitine helps alleviate the heavy, leaden feeling in the limbs that patients often experience during a PEM crash