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In HIV-infected people, fat often accumulates in some areas of the body while it is broken down in other areas, as well as their blood fat percentage (hyperlipidemia) and their insulin resistance, which together leads to a lipodystrophy syndrome

Psychopharmacology (Berl) 2013;230:345352.ArticlePubMed 51

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Data from the surpass trial series revealed that tirzepatide reduces the risk of major adverse cardiovascular events and improves blood pressure, lipid profiles, and inflammatory markers (60, 61)

Or it could be the placebo effect

Chan YH, Chao TF, Chen SW, et al