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In NK cells, exposure to TME downregulates the expression of CD71, CD98, and glucose transporter type 1 (GLUT-1) but elevates the abundance of proteins related to ferroptosis, oxidative damage, and lipid peroxidation (67)

The development of DFU begins with a mechanical injury or pressure on the foot, often due to neuropathy, which impairs the ability to sense pain and prevent tissue damage

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Glutathione: Neutralizes free radicals and provides the skin with an intense, long-lasting radiance