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Yang and co-workers reported a nanomedicine composed of dendritic mesoporous silica nanoparticles (DMSNs), Fe 3 O 4 , Mn, and glutaminase inhibitor Telaglenastat (CB-839) (termed DFMC) for restored oxaliplatin chemosensitivity on the basis of the GSH-responsive and -exhausting effect (Figure 4C) (Wu et al., 2022

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Similar content being viewed by others Background Glutathione is a low molecular weight tri-peptide (-glutamyl-cysteinyl-glycine) found at relatively high concentrations (0.510 mM) in all mammalian cells and relatively low concentrations (220 M) in plasma [1]