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Moreover, TMAO disrupts the renal tubular transport system by inhibiting organic cation and anion transporters (OCTs and OATs), essential for reabsorbing and secreting various compounds in the kidneys (Samodelov et al., 2020)

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[CrossRef] [Google Scholar] Fluorescent derivatization combined with aqueous solvent-based dispersive liquid-liquid microextraction for determination of butyrobetaine, l-carnitine and acetyl-l-carnitine in human plasma

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Citric acid comes from citrus fruits and is an AHA