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Studies indicate that long-term metformin use can reduce serum B12 blood test levels by up to 20%, necessitating regular monitoring and preventive B12 supplementation protocols

However, systematic reviews and randomised controlled trials supporting these claims are notably absent from peer-reviewed literature

doi: 10.1158/1535-7163.MCT-09-0161

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Medical Perspective Slowing cellular aging is about preserving your health from within, while improving the outward signs is only skin deep

It should be handled only by trained personnel using appropriate laboratory procedures and in accordance with institutional safety guidelines