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No clinically relevant findings were observed for laboratory parameters, vital signs or ECG

SGLT2 Inhibition and Renal Urate Excretion: Role of Luminal Glucose, GLUT9, and URAT1

Importantly, glucose metabolism and insulin sensitivity were either unchanged or slightly improved, contrasting with the diabetogenic effects of growth hormone

It is ubiquitously present in mammalian cells and plays a central role in redox balance, cellular detoxification processes, and maintenance of intracellular thiol status

2012;303:E308E321

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