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While several obesity stakeholders still get stuck in the recommendation of BMI alone for obesity definition and risk stratification, thresholds of WC and the addition of the waist-to height ratio within BMI categories would better realize the continuum of risk related to obesities [6, 76, 184]

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The NRF2 inhibitor, ML385, synergizes with silymarin (101), and NRF2 knockdown facilitates S-3'-hydroxy-7',2',4'-trimethoxyisoflavone-mediated ferritinophagy (102), revealing a reciprocal regulatory loop between NRF2 and autophagy

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