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[] Statistical analysis Results were statistically analyzed using the mini-tab statistical program

Sources: Hensley L

88,89,104-106 In contrast, newer agents, such as lubiprostone and elobixibat, act via alternative mechanisms with promising outcomes, specifically through the activation of chloride channel 2 and bile acid transporters

Theres also a lower risk of injury and less pain

Its also not known if the cardioprotective aspects of GLP-1 agonists will be the same with users of orforglipron, and it may take quite some time until that data is available