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Normally, the actions of prooxidant molecules are tightly regulated by antioxidants, achieving an intricate balance that preserves tissue homeostasis, but this balance can be disrupted if ROS exist in overabundance, resulting in oxidative stress [14]

Deng, C

10.1016/S0166-2236(96)80018-X Trends Neurosci

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349 Phenolic compounds in extravirgin olive oil (EVOO), an essential component of the MD, can decrease joint edema, cell migration, cartilage degradation and bone erosion by reducing the levels of proinflammatory cytokines and prostaglandin E2 in the joint

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