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Compared to pioglitazone treatment, rosiglitazone increases the risk of AMI and heart failure in type 2 diabetic patients and elderly patients [222,223,224]

Riddle MC, Forst T, Aronson R, Sauque-Reyna L, Souhami E, Silvestre L, et al

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Residual alcohol entering the vial can interact with the peptide

doi: 10.1016/j.cell.2006.09.024