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GLP-1 plays a key role in digestion and metabolism by helping regulate blood sugar, slowing how quickly food leaves the stomach, and sending signals to the brain that promote feelings of fullness

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Another more widely accepted mechanism entails the dephosphorylation of extracellular NMN into NR by ectonucleotidases (e.g., CD73) prior to its cellular absorption [[162], [163], [164], [165]]

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In the muscle, the mitochondrial and total -oxidation capability in the feeding state were higher in the carnitine supplementation group than in the control, but showed no difference in the fasting state (Fig