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The transcriptional activity of the VDR is regulated not only by binding calcitriol but via the formation of heterodimers with the other nuclear receptors, specifically members of the RXR family

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The study on the brains of the Mecp2-308 mouse model of ASD has shown a reduced ATP production accompanied by a significant reduction in complexes I, II, and V activities in the cerebellum and striatum of the mutant mice [78]