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48 Studies comparing different dosages also found a dose-dependent increase in reduction of homocysteine levels with increasing dose

Natural occurrence : Found naturally in human plasma, saliva, and urine

doi: 10.1200/JCO.2017.35.15_suppl.9536 177 KlemenNDWangMRubinsteinJCOlinoKCluneJAriyanSet al

If thats met at a cost-competitive price with compliant claims and basic QA (clear identity, consistent potency, stable shelf life), a credible middle lane can emerge

Let me break down everything we know so far

Plain creatine monohydrate is the form with virtually all of the research behind it, and no other form has been shown to beat it for results