The research on peptide stability consistently identifies light as a significant degradation factor, second only to temperature
There are two 2HG enantiomers: D-2-hydroxyglutarate (D2HG) and L-2-hydroxyglutarate (L2HG), with the former predominantly generated from IDH1 mutants and PHGDH while L2HG is primarily generated from the promiscuous activity of LDHA and MDH1/2 under hypoxic or acidic conditions and converted back to 2OG by L2HGDH
This is one of the major benefits of Carnitine, and it is precisely why its often found in high-quality post-workout supplements like True Carnitine, that is also known for being an effective assistant in a weight loss process
10.1093/aje/kwac021 Am J Epidemiol
Some people find it mild and more of a nuisance, while for others, it can be quite severe and affect daily activities
may have some nausea the first week, but provided minimal guidance on managing the GI side effects