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The 12 mg trial dose is rarely described in community references because the GI burden was the rate-limiting factor in the trial

10.1007/s00210-024-03199-0 29 DasM.DeviK.A.-O.BelwalT.A.-O.DevkotaH.A.-O.TewariD.SahebnasaghA.et al (2023)

I think its a drug that primary care will have an easier time with than a GLP-1 that is more prone to these side effects

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(2024) A review of therapies for hyperpigmentation modulating the synthesis of eumelanin to pheomelanin, Archives of Dermatological Research, [online]