Translation is the unanswered question
In these two Phase 3 studies (n=3,680 total), patients are randomized to placebo or oral semaglutide in a 1:1 ratio and assessed using the CDR-SB at 2 years, with follow-up of up to 3 years
It is available in effervescent tablets, powder, capsule, and liquid form
These medications, categorized as GLP-1 agonists, were originally approved for the treatment of Type 2 diabetes but have since become popular for their weight-loss benefits
To achieve approval, the medication had to be carefully evaluated by a team of experts to determine that the benefits outweigh the risks for the intended population when used to treat a specific condition
Front Cardiovasc Med 2024, 11: 1413441