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Chronic exposure to PET MPs (0.5400 m, majority 50100 m) over 29 weeks at a dose of 5 mg/week (approximating the relevant annual intake in humans) was investigated in C57BL/6 N mice from peripubertal age to adulthood

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In addition, hydrochlorothiazide, bumetanide and furosemide were also consistently linked to altered blood glucose and impaired glucose tolerance in a variety of animal models (Foy, 1967