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doi: 10.1016/j.bbi.2021.07.009 19 ZhuSHuXFanY

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Variants in JAK2, TYK2, STAT1, STAT3, STAT4 genes increase UC susceptibility [19], and JAK3 knockout mice develop severe combined immunodeficiency, affecting T and B cell development, resulting in IEC differentiation defects and impaired intestinal barrier function, thus increasing susceptibility to UC [131]

Inflammation Reduction: Explored for its ability to mitigate inflammation and oxidative stress

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