Suitable for a range of dietary lifestyles
Muscle loss can be a concern with rapid weight loss, making protein intake essential
Wegovy ~16.9% average body weight loss Boosts metabolic & cardiovascular health Proven, long-established safety profile Weekly injection, easy to use Key Insights on Wegovy and Mood Wegovy and depression concerns have been reported by some patients, although mood-related symptoms remain uncommon in clinical studies
Users often report improved stamina, reduced fatigue, and better physical performance, though these subjective reports have not been validated in controlled human trials
Retatrutide mimics three appetite and metabolic hormones, Mounjaro mimics two, and Wegovy mimics one
Phase 2 data shows retatrutide producing roughly 24% body weight loss versus about 21% for tirzepatide in Phase 3 trials