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For the general structural formula presented above, and reproduced below for ease of reference, there are several different compounds which can be prepared according to the synthesis procedures described above and used for therapies described below

Remarkably, the core motifs of CesA_C2 show a relatively high homology to the second C domain in Vlm1 of the valinomycin NRPS although the overall similarities between the two NRPS is low (approx

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Furthermore, we observed the expression of the well-known membrane-associated FNDC5 and a novel, secretable FNDC5 (sFNDC5) isoform in cells and multiple rat tissues