However, a massive "species gap" exists between humans and rodents regarding uric acid metabolism
These directions are the core support for translating the hypothesis from theory to application and directly determine whether the gut microbiota-ferroptosis axis mechanism can become a breakthrough framework and intervention target in the study of the gut-joint axis in OA (Figures 2, 3)
doi: 10.3389/fncel.2025.1588645 Received 06 March 2025 Accepted 14 April 2025 Published 20 May 2025 Volume 19 - 2025 Edited by Neville Ng, University of Wollongong, Australia Reviewed by Mingzi Zhang, University of Southern California, United States Slawomir Jakiela, Warsaw University of Life Sciences, Poland Vasileios Balis, Aegean College, Greece Updates Copyright 2025 Liu, Sun, Guo, Yuan, Zhu, Lu, Chen, Qu, Feng and Yang
2001 Mar;33(3):205-20
Neuroimaging characteristics of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): a systematic review
HLA-DR reference range is under 25 %, however, we established a cut off level of 35 % to high level of expression, which was not achieved by all patients