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Storage instructions Storage at -20C and Keep from light immediately upon receipt

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Respect the clock: potency drops a little each week past the stability window

That kind of adjustment is one of the clearest, most practical reasons physician-supervised treatment tends to outperform unsupervised prescribing on both comfort and results

These mediators sustain systemic and cutaneous immune activation, and induce the expression of MMPs and TIMPs, as well as of pro-fibrotic genes, thereby promoting inflammation, ECM remodeling and tissue fibrosis [78, 79]

doi: 10.1038/s42255-023-00812-z 44 RetnakaranRYeCEmeryAKramerCKZinmanB