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While the efficacy of levocarnitine to increase carnitine concentrations in patients with ESRD undergoing dialysis has been demonstrated, the effects of supplemental carnitine on the signs and symptoms of carnitine deficiency and on clinical outcomes in this population have not been determined

The resolution timeline is notable

However, its use must be carefully monitored by a dermatologist, as the therapy is still under ongoing research regarding long-term effectiveness and safety

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This technique will often be misleading if steady state has not been reached