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Semaglutide has become popular for diabetes and chronic weight management among patients

Treatment guidelines focus on nutrition, exercise, and pharmacologic therapies to prevent and manage complications

Our obesity rates are higher for those on Medicaid, and we know that handling obesity handles other comorbidities, and we could see a decrease in the overall expense of that patient at the benefit of their health, she says

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In contrast, pathways typically linked to cellular protection, including MYC targets V1, protein secretion, DNA repair, oxidative phosphorylation, the unfolded protein response, MTORC1 signaling, and adipogenesis, were markedly downregulated (Figure 4B and Supplemental Figure 6A)

doi:10.1186/s12951-025-03248-7