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More serious but rare safety considerations include pancreatitis (discontinue if suspected), gallbladder disease, potential thyroid C-cell tumors (based on rodent studies), risk of hypoglycemia when used with insulin or sulfonylureas, and potential for acute kidney injury with severe dehydration

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And simple carbohydrates provide empty calories that crowd out the protein and nutrients you actually need

Research has also linked low glutathione to increased risk of chronic conditions including diabetes, hypertension, and certain liver diseases