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RSPO3 is more associated with hair follicle development, while RSPO4 shows a stronger link to nail growth 6,7

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Semaglutide Therapy and Incidence of Atrial Fibrillation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Diabetes, Obesity & Metabolism, 25(8), 1125-1132

Well a pathognomonic sign for B12 deficiency would have to be applicable to both males and females, wouldn't it

Andersson M, Karumbunathan V, Zimmermann MB

This suggestion is partly based on findings from a randomized trial of 118 patients on isotretinoin that sought to evaluate efficacy of omega-3 in reducing mucocutaneous side effects of isotretinoin