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Reduced glutathione is more active and bioavailable

The study investigated a topical application of GSH-cyclodextrin nanoparticle complex (Glutaryl) as a potential noninvasive GSH delivery route with therapeutic effects against Mycobacterium infection

doi: 10.1158/1078-0432.CCR-08-2262 83 ParkerASHeckmanMGSheininYWuKJHiltonTWDiehlNNet al

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Antihyperalgesia by alpha2-GABA receptors occurs via a genuine spinal action and does not involve supraspinal sites