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Dehydration risk is also higher in older adults, which amplifies the kidney safety advantage of tirzepatide (lower AKI reporting rate)

Mice were housed under 12-h/12-h light/dark cycle, humidity 5060% and 1822 C ambient temperature with free access to food (chow diet, MD17121, Mediscience Ltd, China) and water

Die Inhaltsstoffe sind in mitochondrienreichen Geweben wie Herz und Gehirn natrlicherweise vertreten

Whilst mild cold intolerance is commonly reported during treatment, certain symptoms warrant medical review to exclude underlying conditions such as hypothyroidism or anaemia

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After rinsing, the glass coverslip was transferred to the recording chamber mounted on an inverted microscope (Leica, DMIRB) and continuously superfused with the extracellular medium described above without adding MgSO4 (Mg 2+ ions free medium)