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MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation
Front Endocrinol (Lausanne) 8:197
To harness the protein-degradation activity of this HSP90 chaperone complex, we developed a novel targeted protein degradation technology, termed Chaperone-Mediated Protein Degradation (CHAMP), and an ERK5-CHAMP was designed to induce chemical proximity between HSP90 and ERK5 to induce ERK5 degradation
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As well, 3-HK and 3-HAA were observed to suppress glial cytokine and chemokine expression and attenuated cytokine-induced cell death in primary human fetal CNS cultures [120]
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