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In parallel, obesity-associated low testosterone levels, characterized by reduced total and free testosterone levels, are common in men with obesity, metabolic syndrome, or type 2 diabetes, creating a pre-existing state of diminished anabolic reserve [18]

The range in clinical trials runs from about 25% to 40%, depending on the drug, dose, duration, and whether participants were exercising and eating adequate protein

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Srinivasan S, Stevens M, Wiley JW