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Most aging occurs when the human body is unable to deal with incoming environmental and other unhealthy stresses

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Sulforaphane (a glucosinolate compound found in some cruciferous vegetables like broccoli) is one of the most commonly cited natural Nrf2 activators, though there are many others shown to have similar effects on Nrf2-induced enzymatic activities and metabolites

Colivelin, a synthetic form of the mitochondrial peptide humanin, can suppress STAT3 activation, thereby improving glycocalyx structure and safeguarding endothelial function [77]

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