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The main differences in GLP-1 activity that have been found between males and females are: i) increased weight loss caused by the GLP-1 agonist, liraglutide, in women as compared with men (247)

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The researchers found that people who took a GLP-1 receptor agonist had reduced hip and spine bone mineral density when they didnt exercise, compared to people who took a placebo or just exercised

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In the group of about 650 people taking Contrave, by contrast, there were three cases of stomach paralysis, two bowel obstructions, one case of pancreatitis, and 16 cases of biliary disease