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Irma Ares, Complutense University of Madrid, Spain Updates Copyright 2021 Kirk, Vieson, Selting and Reinhart

Phase I studies from the late 1980s using IGF-1 to treat Larons Syndrome (GH insensitivity) revealed effective increase in linear growth reaching adult heights using doses ranging from 80 to 240 g/kg/day [264268]

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