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10.1152/ajprenal.00489.2016 Am J Physiol Renal Physiol

Gastric acid and digestive enzymes degrade most peptides before absorption can occur

Methionine oxidation Methionine residues are particularly vulnerable to oxidation by dissolved oxygen and reactive oxygen species

[13] In normal circumstances, this metabolite is detoxified by conjugating with glutathione in phase 2 reaction

There exist three Arg metabolic pathways, of which the one producing NO under the catalysis of nitric oxide synthase (NOS) is of the most significance