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2 GPX family and oxidative stress 2.1 GPX1 Glutathione peroxidase 1 (GPX1) was first identified in 1957 as a red blood cell enzyme that protects hemoglobin from oxidative stress ( 2 O 2 and soluble low-molecular hydroperoxides, but not with more complex lipid hydroperoxides

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39 Because belly fat is closely tied to insulin resistance, inflammation, and heart disease risk (the hallmarks of metabolic syndrome), smaller waist circumference suggests that glutathione may help improve not just body composition, but also overall metabolic health

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PMID 12095224